English: Fig. 6: MSOT for determination of the metastatic status of sentinel lymph nodes in melanoma patients. (A) Indocyanine green (ICG) is injected and accumulates inside the sentinel lymph node, which is detected using a hand-held two-dimensional MSOT device. (b) MSOT images of the ICG accumulating in the sentinel lymph node (in color), overlaid on a background image of tissue illuminated at a single wavelength. Each image came from a different patient. (c) MSOT imaging of melanin (in color) overlaid on a background image of tissue. The first image shows a patient without melanoma metastasis. The second image shows a patient with melanoma metastasis inside the sentinel lymph node. In both cases, strong melanin signal from the skin can be seen